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Detalhes da Produção
Tipo | Patente |
Grupo | Produção Técnica |
Descrição | Grossi de Sa, Maria F ; MACEDO, L.L.P. ; SILVA, M. C. M. ; ALMEIDA GARCIA, RAYSSA ; PAULINO SILVA, LUCIANO ; AVILA, A. L., Pesticide. 2018, Brasil. |
Autor | Maria Fatima Grossi de Sa |
Ano | 2018 |
Informações Complementares
Ano de Desenvolvimento | 2018 |
Categoria | Produto e Processo |
Codigo do Registro ou Patente | WO2020007450 |
Data Deposito PCT | 03/07/2018 |
Informações Adicionais | The present invention relates to a process for manufacturing chitosan nanoparticles, which upon RNA is adhered. The process for manufacturing provided provides more stable product, and produces nanopartices with a higher yield. With the nanoparticles with adhered RNA, for example the dsRNAst, provides an efficient method to assist insect-pest control, leading to the plant resistance to insect attack, due to the suppression of target gene(s) expression. The RNA, such as dsRNAst, administered via the nanoparticles is able to penetrate the insect integument, and is also delivered orally when the insect feeds on the sprayed plant, leading to the suppression of the expression of the target gene. The polymer forming the nanoparticle, such as chitosan, may also have the capability to enhance dsRNAst protection against degradation by gut nucleases. They also contribute to the internalization of dsRNAst molecules by insect cells. |
Instituição de Deposito ou Registro | European Patent Office |
Meio de Divulgação | NAO_INFORMADO |
Número Deposito PCT | 2018067922 |
País | Brasil |
Potencial de Inovação | SIM |
Relevância | NAO |
Tipo de Patente | PRIVILEGIO_DE_INOVACAO_PI |
Título | Pesticide |
Título da Patente | Pesticide |
Título(en) | Pesticide |
Grossi de Sa, Maria F | |
Em Domínio Público | |
09012020 | |
SIM |